The new regulations, approved under the Resource Management Act, would see a uniform set of rules applied for the use of the controversial poison.
"This new approach standardises the rules for using such poisons rather than the current system of different rules in different regions.
"This change will reduce costs and delays for operators, ensure consistent conditions throughout the country, reduce mistakes from misunderstanding rule differences and allow best practice approaches to be used."
The change would not increase risks, Smith said, but it was expected to save $11 million over the next 20 years, "enabling more pests to be controlled and more species saved".
The change was advocated for by the Parliamentary Commissioner for the Environment, who was concerned about the duplication and inconsistency of the differing regional rules.
The proposal went out for public consultation with 70 per cent of submissions favouring the change. The new national regulations come into effect on April 1.
Smith made the announcement while visiting the Tiritiri Matangi Sanctuary in the Hauraki Gulf as part of National's annual Bluegreens Forum.
He acknowledged there was opposition to the use of 1080, but said the benefits outweighed the risks.
"I know there is opposition to poisons like 1080 and brodifacoum but they are essential tools to saving New Zealand's natural heritage. Islands like Tiritiri Matangi are only so prolific in birdlife because of the use of these poisons in the past.
"These new regulations will help us create more special sanctuaries for the future and contribute to the Government's goal of a Predator Free NZ by 2050."